6 Natural Tips to Get Rid of Acne and Scars

In many cases, acne and scars can be controlled and prevented. Here we present to you natural tips to get rid of acne and scars

Tea tree oil: It is antibacterial oil which helps in fighting infections and also reducing redness and inflammation.

How to use:

Apply the oil directly to the affected area
Mix it with facewash and let it rest on the face for 20 mins and wash off

Apple cider Vinegar: It helps to get rid of acne and scars and also a good toner. It is an astringent. It also improves blood circulation which helps in healing and regeneration. There are various benefits of apple cider vinegar as it also gives the required pH to the skin.

How to use:

Mix water and apple cider vinegar and apply it on the affected area with a cotton ball. Leave it for 10 mins and wash it with water
Mix honey and apple cider vinegar and apply it with a cotton ball

Lemon Juice: It is a natural antioxidant and possesses bleaching properties. It helps in the formation of collagen and also removing dead skin cells.

How to use:

Apply the fresh juice directly to the affected area with fingertips or cotton ball. Let it rest on the face for 20 mins and wash with warm water. Repeat the procedure daily for up to 3 weeks.
The mixture of honey and lemon is also an effective remedy

Aloe vera: The beneficial effect of this product is known since ages. It helps in the healing process of the acne and scars. It helps in moisturizing and nourishing the skin, giving a glow to the face.

How to use:

Apply fresh aloe vera juice on the affected area and leave it for 30 mins and wash. Use it twice daily to get the beneficial effect.
Many aloe vera formulations are available in the market which diminishes scars, apply as advised on the packing

Baking soda: It is an excellent defoliant which can remove dead skin cells and allows the skin debris to be removed and thus prevents clogging of pores.

How to use:

Mix an equal proportion of water and baking soda to form a thick paste. Apply this paste in the affected area. A gentle massage in circulation helps in exfoliation and removal of dead skin cells. Leave the paste on the skin for 10 mins and rinse it with cold water.

Drink Plenty of Water:

Water is an essential element of the body and is essential to keep the body hydrated for normal functioning. There are various benefits of drinking plenty of water as it helps in flushing of toxins from the body. The toxins in the dehydrated skin can result in acne breakouts. It helps in skin’s natural rejuvenation process. Drink plenty of pure water each day (about 2 liters a day).

It is not just the face which gets affected by the acne; even back acne can be difficult. Here are the tips to prevent back acne

Prevent clogging of pores with sweat and dirt; this is especially important after workout sessions. Take shower immediately to keep the skin clean and hygienic
Use an exfoliator which can also remove dirt and excess oil from the skin
Wear loose clothing
Avoid going in areas of dust and dirt
Longhairs on the back can also be the contributing factor for acne. Shampoo and oiling can clog the sweat pores on the back.
Oil-based creams, lotions, and sunscreen clogs the pores, contributing to back acne
A diet plays an important role in acne breakouts. Diet rich in oils and sugars can contribute to acne. Have a balanced diet of fruits, vegetables, lean protein and whole grains.
These tips to prevent back acne will be very helpful, but in case it is not working; consult a dermatologist who can prescribe oral or topical medications to control back acne.

How To Buy A New Home In Green Bay Wi

Every state has laws that determine the procedure of purchasing a home. Even so, after going through detailed procedures of what happens in luxury real estate companies green bay wi, I realized that it is a fairly manageable process. All you need is to follow a process with five simple steps.
Hiring an agent

This is an essential step for first time home buyers. However, you should note that your choice to hire an agent is determined by the kinds of homes and the areas you are looking to move into. Take the example of open houses and online houses. You barely need an agent to find a home, but if your time is limited, or if you need help finding a home then put a real estate agent to work for you. They will use their fuel, preview homes for you, have the latest list of new homes on the market, know market price points for homes in neighborhoods, and are experts at negotiations, and can guide your through the maze of potential offers and counter offers before you are able to buy your next dream home.

Select on your future home

Choosing your home from new homes for sale bay wi can be quite tiring. There are so many different types of homes on the market. Most of them are undoubtedly beautiful, spacious and in a good location. Chances are you would buy several if you could, but if you are like the average person, you will have to choose just one. Simply ranking homes by important categories like type of home, location of home, and other import things to you can help you narrow your search. This strategy will help you narrow your search, and you will end up with your ideal home. This might take you up to 2 months or more. Also, let your agent help narrow down your search. Remember, they work for you, and let your Realtor help find you homes that meet those search categories! Worst case, you might have to choose between two or three homes, and take several tours of each home just to make sure it’s a perfect fit. But remember, in hot markets, houses do not sit long on the market.

Acquire a loan

You do not always need to get a mortgage or cash from your bank before you get a home. Even so, it is wise to obtain a prequalified loan approval. This also helps you know how much you can afford to pay for a home. Usually, sellers might not even consider your offer unless they are certain that you can obtain a loan for their property. It makes you a serious buyer, and some sellers might be willing to cut you a deal if they know you have the financing. Make sure you shop mortgage rates prior to going with one lender. Check mortgage companies, banks and your local credit union. There are many types of mortgages in the market, and you should make sure you get the best one for you.

Negotiate on the offer

Know what the house is worth in the market, and in the neighborhood. Compare prices of homes for sale by luxury real estate companies green bay wi. Simply bargain the best deal and reach an agreeable price you can afford!

Carry out an inspection

Finally, you should inspect the home. This is crucial because it helps you to know whether the home is perfect for you or whether to home is need of major repairs that you did not identify when touring the home. In Wisconsin, homes sales can be contingent on home inspections, and it allows the seller to fix the problems prior to selling the home, or it allows the buyer to walk away from the home, if the repairs are too much. It is strongly recommended that you get a home inspection, and as important, hiring a good real estate agent that knows how to fill out the forms so you do not get stuck with a lemon of a house.

Methods to Help Immune Cells Identify Cancer Cells Found

The immune cells in the human body are an army that fights pathogens. Whether it is a virus, a bacterium, or a parasite, immune cells can effectively attack most invaders and protect us from disease.

In recent years, scientists have discovered a new application of immune cells—treating cancer. Cancer cells often carry a large number of breakthroughs that may be recognized by immune cells. In order to escape the attack of immune cells, these cancer cells have evolved a series of strategies to disguise themselves as good people.

But these tricks have been gradually seen by scientists. By inhibiting the PD-1/PD-L1 pathway, we can let immune T cells polish their eyes and attack cancer cells. In addition, we can also separate T cells from cancer patients, insert molecules that recognize cancer cells, and then return them to the patient to kill cancer cells.

These treatments using immune cells have achieved remarkable results and have rewritten many treatments for cancer. But scientists also pointed out that the current immunotherapy is concentrated on T cells, slightly monotonous. Be aware that there are many types of immune cells. It would be better if these immune cells can be developed into anti-cancer therapies.

Recently, a study published in Nature Biomedical Engineering, brings us the hope of the emergence of innovative immunotherapy. In this study, scientists have shown that macrophages have an amazing killing effect on cancer in preclinical models.

Macrophages are an important class of immune cells discovered in 1882 by the Russian zoologist Professor élie Metchnikoff. This opened the curtain of human research on the innate immune system, and also helped Professor élie Metchnikoff get the 1908 Nobel Prize in Physiology or Medicine.

As the name suggests, macrophages have a “good appetite” that can phagocytose cell debris, foreign germs, and other pathogens. Although some studies have shown that macrophages can “eat” cancer cells, why can’t they clean the cancer cells when the cancer is just sprouting, and eliminate the disease?

For more than 100 years, as people’s understanding of biology has deepened, we have gradually discovered the reason behind it: in our body, there is indeed a group of macrophages with anticancer activity called M1 macrophages. However, tumors can secrete macrophage colony-stimulating factor (MCSF), “buy” these M1 cells, and turn them into M2 macrophages that turing blind eyes to cancer cells.

What’s worse is that the tumor also expresses a protein called CD47. This protein is like a small sign that says “Don’t eat me”, confusing the macrophages that are not “bought” by cancer cells, letting them put down their weapons.

It is because of this dual mechanism that macrophages cannot effectively attack tumors.

Knowing the reason, direction to solve the problem may then be found. Scientists from the Brigham and Women’s Hospital at Harvard Medical School have designed a miraculous drug that inhibits both the MCSF pathway and the CD47 pathway. According to the design, after the former pathway is inhibited, the proportion of M1 cells that can attack the tumor in macrophages will increase; when the latter pathway is suppressed, the label of cancer cells “don’t eat me” will be torn off. In other words, with this simple drug, bottlenecks met by macrophages in the attack of cancer can be removed at once.

“Our technology can turn M2 cells into M1 cells by inhibiting the M2 signaling pathway,” said Professor Ashish Kulkarni, one of the leaders of the study: “If we can “teach” these macrophages and suppress the label of ‘don’t eat me’, we then can be able to break the balance between M1 cells and M2 cells, increase the proportion of the former, and inhibit tumor growth.”

In theory, this new drug is designed to be perfect. But what is the actual effect? The researchers tested it in animal models of breast cancer and skin cancer. The animals were divided into three groups, one receiving standard anticancer therapy, one receiving this innovative macrophage-targeted drug, and the other receiving no treatment as a control.

As scientists expected, mice that did not receive any treatment produced huge tumors on the 10th day of the experiment, while tumors in mice that received standard anticancer therapy showed a reduction in tumor volume.

Amazingly, therapy targeting macrophages almost completely inhibits tumor growth! In addition, the survival rate of mice has also increased.

“We even saw macrophages phagocytizing cancer cells,” said Professor Shiladitya Sengupta, one of the heads of the study.

This result has excited scientists, and they can’t wait to start the next research and development program. If the study can be repeated in humans, it will undoubtedly add a powerful new army to cancer immunotherapy.